Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases.

ΤίτλοςIdentifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases.
Publication TypeJournal Article
Year of Publication2015
AuthorsAvram A, Duarte C, Santos MJ, Papagoras C, Ritis K, Scarpioni R, Schmidt WA, Skendros P
JournalJoint, bone, spine : revue du rhumatisme
Volume82 Suppl 1
PaginationeS17-29
Date Published2015 Oct
ISSN1297-319X
Abstract

A subgroup of patients with gouty arthritis have a chronic recurring form that is particularly difficult to treat. Such patients experience repeated flares and often have abundant tophi. Many also have underlying comorbidities, such as renal impairment, cardiovascular disease, gastrointestinal disorders, obesity, and hypertension, which contraindicate the use of standard anti-inflammatory medications. Five patients with difficult to treat gouty arthritis who were either candidates and/or treated with anti-IL therapy are described.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S1297-319X(15)30004-X
DOI10.1016/S1297-319X(15)30004-X
Short TitleJoint Bone Spine