The year in cardiology 2015: acute coronary syndromes

"Pathogenesis, early diagnosis, and risk stratification:
Stakos et al. found that the interaction of thrombin-activated platelets with neutrophils at the site of plaque rupture during acute MI results in local NETs formation and delivery of active tissue factor. The notion that NETs represent a mechanism by which neutrophils release thrombogenic signals during atherothrombosis may offer novel therapeutic targets."