A novel mechanism in the regulation of IL-1β-mediated autoinflammation

New data from our group links for the first time environmental stress with inflammation in FMF attack as well as, with other IL-1β-associated autoinflammatory disorders. Stress-induced protein REDD1 is a novel mediator in the pathogenesis of IL-1β-driven inflammation, through regulation of autophagy-mediated release of NETs...read more